Long-read sequencing vs short-read sequencing
WEBJul 26, 2021 · Long-read sequencing. Long-read sequencing technologies are capable of reading longer lengths, between 5,000 and 30,000 base pairs. Therefore, they immediately address one of the main challenges faced by short-read sequencing. They sequence a single molecule, eliminating amplification bias, and …
Homepage - Front Line Genomics
WEBThe Single-Cell and Spatial Buyer's Guide Read more. The Sequencing Buyer’s Guide: 6th Edition Read more. Liquid Biopsy Report – A New Era in Disease Detection and Surveillance Read more. Our mission is to deliver the benefits of genomics to patients faster. We achieve this through website content, articles, reports and events.
A guide to spatial transcriptomics - Front Line Genomics
WEBAug 27, 2021 · A guide to spatial transcriptomics. Immy Mobley 27 August 2021. Today, multi-omics studies have been conducted extensively, revealing information about gene expression changes, cellular function and homeostasis. As a result, all of these processes can now be correlated with disease states and …
Cancer Genomics ONLINE
WEBCancer Genomics ONLINE. When: April 15, 2021 Time: 3:00 pm. The webinar will be available on-demand after this date. REGISTER. The first cancer genome paper was published in 2008, and in just 13 years the power of sequencing and analytics has established genomics as an essential tool in our understanding and treatment of cancers.
Sample Preparation for NGS – A Comprehensive Guide
WEBAug 21, 2024 · Step #3: Amplification. This is an optional step, but it is usually required. It is dependent on the application of NGS and the sample size. Amplification becomes essential to obtain enough coverage for reliable sequencing for samples with small amounts of starting material.
What is multiplex PCR? - Front Line Genomics
WEBJul 26, 2021 · Multiplex PCR is a technique whereby PCR is used to amplify several different DNA sequences simultaneously. It is a type of target enrichment approach. It was first described in 1988 as a method to detect deletion mutations in the dystrophin gene – the largest known human gene. The dystrophin complex connects the …
A brief history of Next Generation Sequencing (NGS)
WEBJul 26, 2021 · 2000: Lynx Therapeutics Company launched the first of the NGS technologies, called Massively parallel signature sequencing (MPSS). The company was later bought by Illumina. 2004: 454 Life Sciences marketed a new generation pyrosequencing technology, called the Roche GS20. It …
A guide to proteomics - Front Line Genomics
WEBAug 27, 2021 · A guide to proteomics. The term ‘proteomics’ was first coined in 1996 by Marc Wilkins, used to define the large-scale analysis of all the proteins in a cell, tissue or organism. The goal of proteomics was to obtain a more wholesome view of biology, as opposed to studying each protein individually. Proteomics has …
DNA Sequencing: How to Choose the Right Technology
WEBAug 6, 2021 · The global market for DNA sequencing is predicted to grow from $15.7 billion in 2021 to $37.7 billion by 2026. The rising prevalence of viral diseases, such as COVID-19, and the increasing cases of cancer globally are likely to drive genomic research and propel the industry at an even more rapid rate.
How to: name a gene - Front Line Genomics
WEBAug 17, 2020 · Protein-coding genes: Named on the basis of a key normal function of the gene product. Gene group members should be designed by Arabic numerals placed immediately after the root symbol, e.g. KLG1, KLF2 and KLF3. Some large families may include a variety of number and letter combinations to indicate subgroupings.