Major League Baseball 's 2025 season begins in Japan on Tuesday, with the Los Angeles Dodgers and Chicago Cubs squaring off at the Tokyo Dome in one of the most anticipated international games ever. “It’s going to be absolutely crazy," Dodgers outfielder Teoscar Hernandez said before the teams left for Japan.

Shohei Ohtani and the reigning World Series champion Los Angeles Dodgers kick off the 2025 Major League Baseball season early Tuesday with the first of a two-game Tokyo Series with the Chicago Cubs.

Playing the Over on runs is a strong bet, as the starting pitchers may not be fully stretched out, and the Tokyo Dome is referred to as “Homer Heaven.” It is a hitter’s park, which can favor the Dodgers against a starter with fly-ball tendencies.