Nick Bosa's hip is an issue. He missed his second practice in a row on Thursday with a hip pointer that he suffered last week in practice. He managed to play through the injury Sunday in Tampa, but he had one of his worst games of the season.

The 49ers do not have tight end George Kittle (hamstring) and edge rusher Nick Bosa (hip) in Wednesday's practice.

San Francisco 49ers defensive end Nick Bosa had his worst game of the season Sunday against the Buccaneers. Turns out he was playing through an extremely painful hip injury that still bothers him -- he sat out Wednesday's practice because of it.

Kyle Shanahan said the 49ers are being smart with George Kittle, and cited Nick Bosa practicing through injury last week.