We encounter, occasionally, parents who are incapable of making medical decisions on behalf of their incompetent or ...

Background Over the last few years, there has been increasing attention to the involvement of the central nervous system in Duchenne muscular dystrophy (DMD). The aim of this study was to assess the ...

The relief of pain and anxiety associated with painful or invasive procedures is a top priority in paediatrics. A ‘Sounding Board’ in the New England Journal of Medicine 30 years ago stated that ‘The ...

Background/aim Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are rare imprinting disorders caused by the aberrant expression of 15q11.2-q13 imprinted genes. Due to their rarity, data on ...

The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled ...

Objectives Background As per the 2023 National Trainees survey, over two-thirds of trainees said they always or often feel worn out at the end of the working day. Objective We tried to understand the ...

Background Infantile hypertrophic cardiomyopathy (HCM) is a heterogeneous disorder. Apart from registries in high-income nations, there is a shortage of data on the aetiological basis of infantile HCM ...

Objectives Develop a score summarising how successfully a child with any surgical condition has been treated, and test the clinical validity of the score. Design Discrete choice experiment (DCE), and ...

Objectives Historically diagnoses of Trisomy 13 (T13) and Trisomy 18 (T18) have been associated with a very poor prognosis. Median survival of full T18 is 14days, T13 is 10days and 3-month survival is ...

Aim DRC software aims to reduce dosing errors, 1 however, it has been linked to ‘alert fatigue’, a phenomenon which causes prescribers to potentially override alerts despite being clinically relevant.

Background Children with autism spectrum disorder (ASD) face unique challenges in acute emergency presentations, resulting in longer wait times, heightened distress, and communication barriers.

Objectives Neurodevelopmental Disorders (NDD) often co-exist with a wider range of emotional, behavioural, and intellectual disorders, collectively grouped together as NDEBID. The commonest NDD are ...