This important work shows how a simple geophysical setting of gas flow over a narrow channel of water can create a physical environment that leads to the isothermal replication of nucleic acids. The ...

In sum, odors initiate feeding behavior in Drosophila.

A core task in single-cell data analysis is recovering the latent dimensions encoding the genetic and epigenetic landscapes inhabited by cell types and lineages. However, consensus is lacking for ...

Cortices from 11 primate species share the same archetypal fractal shape, indicating a universal mechanism for primate and mammalian cortical folding, and suggesting novel shape biomarkers for brains.

A complex extracted from the amniotic membrane in humans reduces post-surgical pain in mice by directly inhibiting pain-sensing neurons.

A critical review of the limitations posed by current preclinical animal models of Alzheimer's disease and of the oversimplistic assumptions proposed by the amyloid cascade hypothesis (ACH).

A primary constraint for mitochondrial repression is access to cytosolic inorganic phosphate, which is determined by the glycolytic flux rate.

Here, we show that the timing of blastomere polarization at the 8-cell stage is asynchronous, and that the heterogeneity between the blastomeres at the 4-cell stage influences cell fate specification ...

A calcium transient measurement system utilizing human induced pluripotent stem cell-derived cardiomyocytes reveals the detrimental impact of inflammatory cytokines on cardiomyocyte relaxation and ...

The raw mass spectrometry data was deposited in the PRIDE repository:Project Name: Spatially restricted proteomics reveals dynamic changes in the caveolin-1 interactome in response to increased membra ...

A tailored cocktail of genes can reprogram a subset of progenitors to no longer produce glial cells and instead develop into neurons involved in motor control.

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