Intensive Care Unit, John Radcliffe Hospital, Oxford OX3 9DU, UK Correspondence to: Dr C S Garrard, Intensive Care Unit, John Radcliffe Hospital, Oxford OX3 9DU, UK; chris.garrard{at}clinical-medicine ...

2 Guy's and St Thomas' Foundation NHS Trust, London, UK 3 Greenwich Primary Care Trust, London, UK 4 Croydon Primary Care Trust, London, UK Background The COPD (chronic obstructive pulmonary disease) ...

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1 Centre for Respiratory Failure and Sleep Disorders, Royal Prince Alfred Hospital, Sydney, NSW 2050 and Institute of Respiratory Medicine, University of Sydney, NSW 2006, Australia 2 Human Nutrition ...

Rationale/Objectives Despite plausible pathophysiological mechanisms, research is needed to confirm the relationship between sleep, circadian rhythm and delirium in patients admitted to the intensive ...

Objective Anaesthesiology guidelines suggest that opioids worsen obstructive sleep apnoea (OSA) despite no randomised controlled trial evidence. We therefore conducted a randomised controlled trial to ...

Of 49 patients undergoing operation for benign spontaneous pneumothorax, 28 (57%) were found to have a sharp first or second rib. In a series of 100 patients undergoing thoracotomy for other ...

Rationale Endoscopic lung volume reduction improves lung function, quality of life and exercise capacity in severe emphysema patients. However, its effect on the diaphragm function is not well ...

Background: The load imposed on ventilation by increased body mass contributes to the respiratory symptoms caused by obesity. A study was conducted to quantify ventilatory load and respiratory drive ...

2 Department of Pulmonary and Cardiac Rehabilitation, Coventry University, School of Health and Life Sciences, Coventry, UK 3 Clinical Trials Unit, Warwick Medical School, The University of Warwick, ...

A structural and metabolic framework for classifying pre-clinical tuberculosis infection phenotypes using 18F-FDG PET-CT: a prospective cohort analysis following M. tuberculosis exposure ...

3 Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada Correspondence to Dr Pierre Ernst, Centre for Clinical Epidemiology, ...