The Krebs cycle byproduct itaconate regulates immune cell function, however its role within tumor cells remains unclear. Here ...
In this issue, Papismadov et al (2024) report that p21 (CDKN1A), known to activate the senescence growth arrest, also ...
Evidence suggests mitochondrial homeostasis plays a role in autism spectrum disorders (ASDs), but the causal relationships ...
NOD2-mediated physiological inflammation is critical for maintaining intestinal homeostasis. The deubiquitinating enzyme YOD1 ...
The systemic regulation of metabolic dysfunction-associated liver disease remains poorly understood. In this issue, Hsiao et ...
The liver function in post-cardiac arrest brain injury is not known and was investigated in a pig model of global cerebral ...
The time bomb of misinformation and disinformation will have exploded, taking with it our ability to think for ourselves.
Astrocytes in the brain exhibit significant regional diversity, but the mechanisms controlling their heterogeneity remain ...
Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The nucleoskeleton is essential for nuclear ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. While mechanisms controlling uncoupling ...