Background and objective Prior studies have suggested that patients with premature ventricular complexes (PVCs) may have an ...

Milestone articles have highlighted the frequency and types of statistical errors in research,1–5 yet fundamental errors ...

Background Mobility limitation is prevalent in patients with heart failure (HF), but the dose-response relationship between ...

Legalisation of medical and recreational cannabis commerce is spreading around the world, associated with increased use1 and falling perception of the risk.2 Frequent cannabis use has increased in ...

Background Emerging evidence suggests associations between air pollution, multimorbidity, and atrial fibrillation (AF), but their interplay remains unclear. We evaluated these relationships in a ...

Introduction Bicuspid aortic valve (BAV) affects 1% of the general population. NOTCH1 was the first gene associated with BAV. The proportion of familial and sporadic BAV disease attributed to NOTCH1 ...

CT-derived fractional flow reserve (CT-FFR) uses computational fluid dynamics to derive non-invasive FFR to determine the haemodynamic significance of coronary artery lesions. Studies have ...

5 Department of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore 6 Department of Cardiology, National University Heart Centre, Singapore Objective To investigate the prognostic ...

Objectives This updated hierarchical Bayesian meta-analysis aims to integrate the latest randomised controlled trials (RCTs) on the use of cerebral embolic protection (CEP) in transcatheter aortic ...

Objectives (1) Describe how the risk of major adverse cardiovascular events (MACE) in individuals with chronic myeloid leukaemia (CML) has evolved; (2) evaluate the risk of MACE associated with the ...

In his song ‘Envelhecer’ (‘Aging’), Arnaldo Antunes states that “the most modern thing there is in this life is to grow old”.1 In this piece, he reframes aging not only as an inevitable biological ...

### Learning objectives Specialist outpatient clinics were first established by cardiologists with a broader involvement in valve disease including inpatient opinions and care (figure 1).1 2 This ...