Combination rituximab and IVIG therapy may be a viable treatment option for patients with refractory autoimmune diseases, though the quality of evidence is low.

For mothers with opioid use disorder (OUD), treatment with buprenorphine in pregnancy is associated with improved maternal and infant outcomes.

Patients with at least 5 comorbidities had worsened pain and functional scores compared with patients with 3 comorbidities at 12 months following TKA.

For patients with metabolic dysfunction-associated steatohepatitis (MASH) and fibrosis, semaglutide is associated with improved liver histologic outcomes.

Among patients with acute LBP, use of nonpharmacologic therapy was associated with reduced risk for overdose-related hospitalizations.

Urinary incontinence is not associated with moderate-to-vigorous physical activity (MVPA) classification, but is associated with cardiovascular disease (CVD) risk factors and comorbidity.

Metformin and SGLT2 inhibitors are associated with similar rates of incident gout among patients with type 2 diabetes.

Patients with vs without RA have a higher risk for avoidable hospitalizations for ambulatory care sensitive conditions, particularly heart failure and pulmonary edema.