Open Heart. is an open access journal by BMJ and BCS, publishing original research in cardiovascular medicine. Impact Factor: 2.8 Citescore: 4.6 All metrics >>

Mar 2, 2021 · The past two decades have heralded dramatic improvements in outcomes for people living with heart failure with reduced ejection fraction (HFrEF). 1 The more widespread implementation of disease modifying pharmacological therapies,2 supported by landmark trials of renin-angiotensin system inhibitors3 and beta-blockers4 have improved longevity despite a background of an ageing and increasingly ...

An open access cardiology journal publishing original research and opinion on cardiovascular medicine at all study phases.

Apr 27, 2021 · The field of transcatheter mitral valve repair (TMVr) for mitral regurgitation (MR) is rapidly evolving. Besides the well-established transcatheter mitral edge-to-edge repair approach, there is also growing evidence for therapeutic strategies targeting the mitral annulus and mitral valve chordae. A patient-tailored approach, careful patient selection and an experienced interventional team is ...

Nov 9, 2024 · Introduction. Myocarditis is an inflammatory process of the myocardium, and the most common cause is a viral infection such as influenza or coronaviruses.1 While most cases of viral myocarditis are mild with good prognosis, life-threatening cardiac dysfunction and arrhythmias may occur.2 3 Myocarditis can result in heart failure and sudden cardiac death and has been recognised as a rare ...

Nov 13, 2024 · In the current issue of Open Heart, the study by Butler and colleagues completed a much-needed investigation that provides valuable insights into the risk of developing incident myocarditis in the general population following COVID-19 or influenza infection. The authors used a large, USA-based administrative health claims database to complete a retrospective analysis of the risk of myocarditis ...

Sep 5, 2020 · Ivermectin, on the WHO’s List of Essential Medications, has been in clinical use since 1981 as an orally and topically active agent for treating a range of parasitic infections in humans, including river blindness and lymphatic filariasis. It …

Mar 8, 2022 · COVID-19 postvaccination myocarditis. To end the COVID-19 pandemic, vaccination is an essential component of the public health strategy. Large, randomised controlled trials of COVID-19 vaccines were found safe and effective in preventing laboratory-confirmed symptomatic COVID-1924–26; even though, adverse effects have been reported.In the specific group population of young adults and ...

Edited by Anastasia Shchendrygina, Clara Ines Saldarriaga Revolutionary improvements in heart failure (HF) treatment have been made in recent years, including the introduction of novel therapies like SGLT-2 inhibitors for HF with preserved ejection fraction (HFpEF). However, further research is needed on implementing these therapies worldwide, addressing challenges in …

Mar 8, 2024 · Objective Coronary CT angiography (CCTA) permits both qualitative and quantitative analysis of atherosclerotic plaque and may be a suitable risk modifier in assessing patients at intermediate risk of atherosclerotic cardiovascular disease. We sought to determine the association of plaque components with long-term major adverse cardiovascular events (MACEs) in asymptomatic intermediate-risk ...